SCNN1B Antibody is a Rabbit Polyclonal antibody against SCNN1B. SCNN1B, also named as SCNEB, ENaCB, Beta-NaCH and Beta-ENaC, belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family and SCNN1B subfamily. Sodium permeable non-voltage-sensitive ion channel is inhibited by the diuretic amiloride. SCNN1B mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. It controls the reabsorption of sodium in kidney, colon, lung and sweat glands. SCNN1B plays a role in taste perception.

Target	Amiloride-Sensitive Sodium Channel Subunit Beta (SCNN1B)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 406-640 of human SCNN1B.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51168 (UniProt, ExPASy)
UniProt Secondary AC	C5HTZ2, O60891, Q96KG2, Q9UJ32, Q9UMU5
UniProt Entry Name	SCNNB_HUMAN
Gene Symbol	SCNN1B
GeneID	6338
NCBI Accession	NP_000327.2
KEGG	hsa:6338
String	9606.ENSP00000345751
Molecular Weight	Calculated MW: 73 kDa Observed MW: 75 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Amiloride-Sensitive Sodium Channel Subunit Beta (SCNN1B)