This product is a bulk custom formulation of the abx033319 antibody.

SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Target	Alpha-1-Antichymotrypsin (SERPINA3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 282-310 amino acids from the C-terminal region of human SERPINA3.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P01011 (UniProt, ExPASy)
UniProt Secondary AC	B3KVQ7, Q13703, Q2TU87, Q2TU88, Q59GP9, Q6LBY8, Q6LDT7, Q6NSC9, Q8N177, Q96DW8, Q9UC47, Q9UNU9
UniProt Entry Name	AACT_HUMAN
Gene Symbol	SERPINA3
GeneID	12
OMIM	107280
NCBI Accession	NP_001076.2 NM_001085.4
HGNC	16
KEGG	hsa:12
Ensembl	ENSG00000196136
String	9606.ENSP00000450540
Molecular Weight	Calculated MW: 47.7 kDa
Buffer	PBS containing 0.09% sodium azide.
Concentration	5 mg/ml
Availability	Shipped within 10-20 working days.
Note	This product is for research use only.

Research Articles on Alpha-1-Antichymotrypsin (SERPINA3)