產品詳情
簡單介紹：
Anti-AADAT antibody (34-429) (STJ115057)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB/IHC/IF |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-AADAT (34-429) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:2000-1:4000 IHC-P 1:50-1:200 IF/ICC 1:50-1:200 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | AADAT |
| Gene ID: | 51166 |
| Uniprot ID: | AADAT_HUMAN |
| Immunogen Region: | 34-429 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 34-429 of human AADAT (NP_001273611.1). |
| Immunogen Sequence: | PKSMISLAGGLPNPNMFPFK TAVITVENGKTIQFGEEMMK RALQYSPSAGIPELLSWLKQ LQIKLHNPPTIHYPPSQGQM DLCVTSGSQQGLCKVFEMII NPGDNVLLDEPAYSGTLQSL HPLGCNIINVASDESGIVPD SLRDILSRWKPEDAKNPQKN TPKFLYTVPNGNNPTGNSLT SERKKEIYELARKYDFLIIE DDPYYFLQFNKFRVPTFLSM DVDGRVIRADSFSKIISSG |
| Tissue Specificity | Higher expression in the liver. Also found in heart, brain, kidney, pancreas, prostate, testis and ovary. |
| Function | Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro). |
| Protein Name | Kynurenine/Alpha-Aminoadipate Aminotransferase - Mitochondrial Kat/Aadat 2-Aminoadipate Aminotransferase 2-Aminoadipate Transaminase Alpha-Aminoadipate Aminotransferase Aadat Glycine Transaminase Aadat Kynurenine Aminotransferase Ii Kynurenine--Glyoxylate Transaminase Aadat Kynurenine--Oxoglutarate Aminotransferase Ii Kynurenine--Oxoglutarate Transaminase 2 Kynurenine--Oxoglutarate Transaminase Ii Methionine--Glyoxylate Transaminase Aadat |
| Database Links | Reactome: R-HSA-71064 Reactome: R-HSA-71240 |
| Cellular Localisation | Mitochondrion |
| Alternative Antibody Names | Anti-Kynurenine/Alpha-Aminoadipate Aminotransferase - Mitochondrial antibody Anti-Kat/Aadat antibody Anti-2-Aminoadipate Aminotransferase antibody Anti-2-Aminoadipate Transaminase antibody Anti-Alpha-Aminoadipate Aminotransferase antibody Anti-Aadat antibody Anti-Glycine Transaminase Aadat antibody Anti-Kynurenine Aminotransferase Ii antibody Anti-Kynurenine--Glyoxylate Transaminase Aadat antibody Anti-Kynurenine--Oxoglutarate Aminotransferase Ii antibody Anti-Kynurenine--Oxoglutarate Transaminase 2 antibody Anti-Kynurenine--Oxoglutarate Transaminase Ii antibody Anti-Methionine--Glyoxylate Transaminase Aadat antibody Anti-AADAT antibody Anti-KAT2 antibody Anti-KYAT2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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