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  • 產(chǎn)品名稱(chēng)：Anti-AANAT antibody (1-207) (STJ113429)

  • 產(chǎn)品型號(hào)：STJ113429
  • 產(chǎn)品廠商：ST john's laboratory
  • 產(chǎn)品文檔：
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Anti-AANAT antibody (1-207) (STJ113429)
詳情介紹：
Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-AANAT (1-207) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: AANAT
Gene ID: 15
Uniprot ID: SNAT_HUMAN
Immunogen Region: 1-207
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-207 of human AANAT (NP_001079.1).
Immunogen Sequence: MSTQSTHPLKPEAPRLPPGI PESPSCQRRHTLPASEFRCL TPEDAVSAFEIEREAFISVL GVCPLYLDEIRHFLTLCPEL SLGWFEEGCLVAFIIGSLWD KERLMQESLTLHRSGGHIAH LHVLAVHRAFRQQGRGPILL WRYLHHLGSQPAVRRAALMC EDALVPFYERFSFHAVGPCA ITVGSLTFMELHCSLRGHPF LRRNSGC
Tissue Specificity Highly expressed in pineal gland and at lower levels in the retina. Weak expression in several brain regions and in the pituitary gland.
Post Translational Modifications cAMP-dependent phosphorylation on both N-terminal Thr-31 and C-terminal Ser-205 regulates AANAT activity by promoting interaction with 14-3-3 proteins.
Function Controls the night/day rhythm of melatonin production in the pineal gland. Catalyzes the N-acetylation of serotonin into N-acetylserotonin, the penultimate step in the synthesis of melatonin.
Protein Name Serotonin N-Acetyltransferase
Serotonin Acetylase
Aralkylamine N-Acetyltransferase
Aa-Nat
Database Links Reactome: R-HSA-209931
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Serotonin N-Acetyltransferase antibody
Anti-Serotonin Acetylase antibody
Anti-Aralkylamine N-Acetyltransferase antibody
Anti-Aa-Nat antibody
Anti-AANAT antibody
Anti-SNAT antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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