產(chǎn)品詳情
簡單介紹：
Anti-FN3K antibody (1-200) (STJ115680)
詳情介紹：
| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: | Rabbit polyclonal antibody anti-FN3K (1-200) is suitable for use in Western Blot research applications. |
| Clonality: | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:500-1:2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FN3K |
| Gene ID: | 64122 |
| Uniprot ID: | FN3K_HUMAN |
| Immunogen Region: | 1-200 |
| Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FN3K (NP_071441.1). |
| Immunogen Sequence: | MEQLLRAELRTATLRAFGGP GAGCISEGRAYDTDAGPVFV KVNRRTQARQMFEGEVASLE ALRSTGLVRVPRPMKVIDLP GGGAAFVMEHLKMKSLSSQA SKLGEQMADLHLYNQKLREK LKEEENTVGRRGEGAEPQYV DKFGFHTVTCCGFIPQVNEW QDDWPTFFARHRLQAQLDLI EKDYADREARELWSRLQVKI |
| Tissue Specificity | Widely expressed. Expressed in erythrocytes. |
| Function | Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate. Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions. Involved in intracellular deglycation in erythrocytes. Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function. Also able to phosphorylate psicosamines and ribulosamines. |
| Protein Name | Fructosamine-3-Kinase Protein-Psicosamine 3-Kinase Fn3k Protein-Ribulosamine 3-Kinase Fn3k |
| Database Links | Reactome: R-HSA-163841 |
| Alternative Antibody Names | Anti-Fructosamine-3-Kinase antibody Anti-Protein-Psicosamine 3-Kinase Fn3k antibody Anti-Protein-Ribulosamine 3-Kinase Fn3k antibody Anti-FN3K antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
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